The NICE British National Formulary (BNF) and British National Formulary for Children (BNFc) sites are only available to users in the UK, Crown Dependencies and British Overseas Territories. If you believe you are seeing this page in error please contact us. Read the Patient Information Leaflet if available from your pharmacist before you start taking fluconazole and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually once daily. If you are taking the liquid suspension form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Dosage is based on your medical condition and response to treatment. Generally in children, the dose should not exceed 600 milligrams daily unless directed by the doctor.
This leaflet is about the use of fluconazole for the treatment and prevention of certain yeast and fungal infections. This leaflet has been written specifically for parents and carers about the use of this medicine in children. Our information sometimes differs from that provided by the manufacturer, because their information is usually aimed at adult patients. Keep it somewhere safe so that you can read it again. Fluconazole Brand names: Diflucan® Your child has an infection caused by a yeast or fungus. Fluconazole causes damage to the membrane of yeast and fungal cells and stops the cells growing and multiplying. This gets rid of the infection, or stops an infection from developing. Some of the yeast or fungus may remain after the infection has gone. However, in babies this may be once every two or three days. Call your doc and he should be able to call in another dose for you. It helps to relieve the pain of the sores in your mouth. I've been in doctors offices, grocery stores, and around small children. I've been living with my mom for a year and now she is getting down very sick. This is basically a repeat of what happened to me and my dad on the farm. Doctors are not listening to me or taking anything I say seriously. They aren't running tests because they do not believe there's anything to find. over the last few months, my medic tried ketoconazole (for months), nystatin (2 full 10 day courses), and gentian violet (for about 4-5 days) - with no results... then i tried 100mg daily for 10 days of fluconazole, the symptoms started to rapidly fade, then slowly taper to near non-existence toward the 10th day. then i moved to itraconazole, it looks like 400-500mg daily for 10 days. I had regular candida infections which my dr prescribed fluconazole for a few times over the years which I suspect is from the overuse of antibiotics and now I have candida glabrata as of earlier this year which my dr has only prescribed my fluconazole for (I know from reading on this it is not the correct treatment and am visiting my dr soon to discuss. I've heard with the candida glabrata it usually affects immunicompromized people which scares me more.
150 mg orally as a single dose Infectious Diseases Society of America (IDSA) Recommendations: -Uncomplicated vaginitis: 150 mg orally as a single dose -Management of recurrent vulvovaginal candidiasis (after 10 to 14 days induction therapy): 150 mg orally once a week for 6 months -Complicated vulvovaginal candidiasis: 150 mg orally every 72 hours for 3 doses US CDC Recommendations: -Uncomplicated vulvovaginal candidiasis: 150 mg orally as a single dose -Initial therapy for recurrent vulvovaginal candidiasis: 100 to 200 mg orally every 72 hours for 3 doses -Maintenance therapy for recurrent vulvovaginal candidiasis: 100 to 200 mg orally once a week for 6 months -Severe vulvovaginal candidiasis: 150 mg orally every 72 hours for 2 doses US CDC, National Institutes of Health (NIH), and IDSA Recommendations for HIV-infected Patients: -Uncomplicated vulvovaginal candidiasis: 150 mg orally as a single dose -Severe or recurrent vulvovaginal candidiasis: 100 to 200 mg orally once a day for at least 7 days -Suppressive therapy for vulvovaginal candidiasis: 150 mg orally once a week Comments: -Recommended as preferred therapy -Unless frequent or severe recurrences, suppressive therapy generally not recommended Oropharyngeal candidiasis: 200 mg IV or orally on the first day followed by 100 mg IV or orally once a day Duration of therapy: At least 2 weeks, to reduce the risk of relapse IDSA Recommendations: -Moderate to severe oropharyngeal candidiasis: 100 to 200 mg IV or orally once a day for 7 to 14 days Comments: -Recommended as primary therapy US CDC, NIH, and IDSA Recommendations for HIV-infected Patients: -Initial episodes of oropharyngeal candidiasis: 100 mg orally once a day for 7 to 14 days -Suppressive therapy for oropharyngeal candidiasis: 100 mg orally once a day or 3 times a week Comments: -Recommended as preferred oral therapy -Unless frequent or severe recurrences, suppressive therapy generally not recommended Doses up to 400 mg/day have been used. Comments: -Optimal therapeutic dose and therapy duration have not been established. Use: For systemic Candida infections including candidemia, disseminated candidiasis, and pneumonia IDSA Recommendations: Candidemia in nonneutropenic or neutropenic patients: 800 mg IV or orally on the first day followed by 400 mg IV or orally once a day Duration of therapy: -Nonneutropenic patients: 14 days after first negative blood culture and candidemia signs/symptoms resolve -Neutropenic patients: 2 weeks after Candida cleared from bloodstream (documented) and candidemia symptoms and neutropenia resolve Chronic disseminated candidiasis in stable patients: 400 mg IV or orally once a day Duration of therapy: Until lesions have resolved (usually months) and through periods of immunosuppression Candida osteoarticular infection: 400 mg IV or orally once a day Duration of therapy: -Osteomyelitis: 6 to 12 months -Septic arthritis: At least 6 weeks CNS candidiasis (after initial regimen of IV amphotericin B): 400 to 800 mg IV or orally once a day Duration of therapy: Until all signs/symptoms and CSF and radiologic abnormalities resolve Candida cardiovascular system infection: 400 to 800 mg IV or orally once a day Duration of therapy: -Endocarditis: Lifelong suppressive therapy may be indicated. -Pericarditis or myocarditis: Often several months -Suppurative thrombophlebitis: At least 2 weeks after candidemia cleared -Infected pacemaker, implantable cardioverter defibrillator (ICD), or ventricular assist device (VAD): 4 to 6 weeks after device removed; chronic suppressive therapy if VAD not removed Comments: -Candidemia in nonneutropenic patients: Recommended as primary therapy; an echinocandin is recommended for moderately severe to severe illness or recent azole exposure; switching to this drug after initial echinocandin is often appropriate. -Candidemia in neutropenic patients: Recommended as alternative therapy; an echinocandin or IV amphotericin B preferred for most patients; this drug recommended for patients without recent azole exposure and who are not critically ill. -Recommended as primary therapy for chronic disseminated candidiasis in stable patients, Candida osteoarticular infection, CNS candidiasis, pericarditis/myocarditis, and suppurative thrombophlebitis -Recommended as alternative therapy for endocarditis and infected pacemaker, ICD, or VAD Doses up to 400 mg/day have been used. Comments: -Optimal therapeutic dose and therapy duration have not been established. Fluconazole is indicated in the treatment of mycoses caused by Candida, Cryptococcus and other susceptible yeast, in particular: 1. The treatment of partners who present with symptomatic genital candidiasis should be considered. Prevention of fungal infections in patients predisposed to such infections as a result of chemotherapy or radiotherapy, including bone transplant patients. Dermatomycosis, including infections such as Tinea pedis, Tinea corporis, Tinea cruris, Tinea versicolor. Mucosal candidiasis: These include oropharyngeal candidiasis, oesophageal, non-invasive bronchopulmonary infections, candiduria, mucocutaneous candidiasis and chronic atrophic oral candidiasis (denture sore mouth). Fluconazole is not indicated for nail infections and tinea capitis. Consideration should be given to official guidance on the appropriate use of antimycotic agents. Both normal hosts and immunocompromised patients may be treated. Before initiating treatment, samples should be taken for microbiological analysis and the suitability of the therapy should be subsequently confirmed (see sections 4.2 and 5.1) In some patients with severe crytococcoal meningitis, the mycological response during fluconazole treatment may be slower that during other treatments (see section 4.4) The daily dose of fluconazole will depend on the nature and severity of the fungal infection. 2 Systemic candidiasis (including disseminated deep infections and peritonitis). Acute cryptococcal meningitis in adults, including patients with AIDS, transplanted patients or other patients with other causes of immunosuppression. Most cases of vaginal candidiasis respond to a single dose treatment. The treatment of those types of infection requiring multiple doses of the drug should be continued until the clinical parameters or laboratory tests indicate that the active fungal infection has subsided. An inadequate treatment period may cause relapses of the active infection. Patients with AIDS and cryptococcal meningitis or recurrent oral candidiasis usually require maintenance treatment to prevent relapses.
Fluconazole official prescribing information for healthcare professionals. Includes indications, dosage, adverse reactions, pharmacology and more. By mouth. For Child. 150 mg for 1 dose, for use in patients who are post-puberty. Medicines for Children leaflet Fluconazole for yeast and fungal infections.