In the aftermath of disaster, you evacuate your home with your family and your bug-out bag. For one reason another, you overlooked swapping out your three year old medications and now are faced with a dilemma. I am not a medical professional but everything that I have read says, yes, they are not only safe but that the expiration dates on drugs as printed or stamped on those bottles represent more of a CYA for the manufacturers than any thing else. According to the Harvard Medical School Family Health Guide: Most of what is known about drug expiration dates comes from a study conducted by the Food and Drug Administration at the request of the military. With a large and expensive stockpile of drugs, the military faced tossing out and replacing its drugs every few years. What they found from the study is 90% of more than 100 drugs, both prescription and over-the-counter, were perfectly good to use even 15 years after the expiration date. So the expiration date doesn’t really indicate a point at which the medication is no longer effective or has become unsafe to use. Medical authorities state expired drugs are safe to take, even those that expired years ago. TORONTO -- The recall earlier this week of a batch of Alesse birth control pills sold past their expiry date has raised questions about whether it's safe to take over-the-counter and prescription medications beyond their best-before marker -- and just how long past? "I think it would alarm a lot of Canadians if they knew that there isn't a lot of study on this," said Phil Emberley, director of pharmacy innovation at the Canadian Pharmacists Association. Drug manufacturers must provide evidence on the potency and safety of products related to exposure to light, heat and humidity in order to get market approval from Health Canada, using what are known as stability studies. "The purpose of the stability study is to establish, based on testing a minimum of three batches of the drug product, a shelf life and label storage instructions applicable to all future batches of the drug product manufactured and packaged under similar circumstances," Health Canada says. These tests include studies in which pilot batches of medications are stored at a temperature of about 25 C, with about 60 per cent relative humidity, for a minimum of 12 months, the federal department says on its website. The expiration date is the final date that a manufacturer will guarantee 100 per cent potency and safety of a medication, based on stability testing under Health Canada's good manufacturing practices, or GMP. But that best-before date is based on an unopened container.
HSV and VZV infections are opportunistic infections (OIs) of HIV. An OI is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as people with HIV—than in people with healthy immune systems. Off-label use, for example, can include using a drug for a different disease or medical condition. Good medical practice and the best interests of a patient sometimes require that a medicine be used off-label. The guidelines include recommendations on the following uses of valacyclovir hydrochloride: On-label uses: The above list may not include all of the HIV-related uses of valacyclovir hydrochloride recommended in the guidelines. Some recommended uses, such as uses in certain rare circumstances, may have been omitted. Take valacyclovir hydrochloride according to your health care provider’s instructions. Your health care provider will tell you how much valacyclovir hydrochloride to take and when to take it. Valaciclovir, also spelled valacyclovir, is an antiviral drug used in the management of herpes simplex, herpes zoster (shingles), and herpes B. It is a prodrug, which is converted to aciclovir in a persons body. Common adverse drug reactions (≥1% of patients) associated with valaciclovir therapy are the same as for aciclovir, its active metabolite, and include: nausea, vomiting, diarrhea and headache. Infrequent adverse effects (0.1–1% of patients) include: agitation, vertigo, confusion, dizziness, edema, arthralgia, sore throat, constipation, abdominal pain, rash, weakness and/or renal impairment. Rare adverse effects ( Valaciclovir belongs to a family of molecules first described and patented by Paolo Cornaglia Ferraris in 1982 (patents EP0077460 A2, CA1258149A1, DE3273785D1, EP0077460A3, EP0077460B1, US4567182). Valaciclovir is a prodrug, an esterified version of aciclovir that has greater oral bioavailability (about 55%) than aciclovir (10–20%). It is converted by esterases to the active drug aciclovir, as well as the amino acid valine, via hepatic first-pass metabolism.
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Usual time frame for the blisters to turn into scabs and then the scabs to heal is 5-12 days. Read more Usually "beyond use" date is printed on the pharmacy container at dispensing. Each med is different and some meds should not be used beyond "expiration." for example: insulin, epinephrine, nitroglycerine and vaccines lose potency beyond their dates. Read more It is never a good idea to take medications that are expired. Most medicines are usually good far beyond those dates. However, with a vast majority of medications, it should be noted that the expiration date on the package does not mean the product is rendered useless the day after the expiration date. If within a few days of the expiration date, i suggest contacting your pharmacist for an opinion.
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