Sertraline is indicated for the treatment of: Major depressive episodes. Prevention of recurrence of major depressive episodes. Obsessive compulsive disorder (OCD) in adults and paediatric patients aged 6-17 years. Post traumatic stress disorder (PTSD) Depression and OCD Sertraline treatment should be started at a dose of 50 mg/day. Panic Disorder, PTSD, and Social Anxiety Disorder Therapy should be initiated at 25 mg/day. After one week, the dose should be increased to 50 mg once daily. This dosage regimen has been shown to reduce the frequency of early treatment emergent side effects characteristic of panic disorder. Depression, OCD, Panic Disorder, Social Anxiety Disorder and PTSD Patients not responding to a 50 mg dose may benefit from dose increases. Dose changes should be made in steps of 50 mg at intervals of at least one week, up to a maximum of 200 mg/day. Sertraline hydrochloride is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI). It works by enhancing the activity of a neurotransmitter called serotonin in the brain. Neurotransmitters are natural body chemicals that act as chemical messengers between the nerve cells. Serotonin is a neurotransmitter known to be involved in regulating emotions, mood and behaviour, among other things. In depression and anxiety disorders there is a decreased amount of serotonin released from nerve cells in the brain. Sertraline works by stopping the serotonin that has been released from being reabsorbed back into the nerve cells in the brain. This helps to prolong its effects and over time this helps to lighten mood and relieve depression.
Hi Selective serotonin reuptake inhibitors (SSRIs) are the drug of choice for OCD. The common SSRIs include fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil) and fluvoxamine (Luvox). The main indication for SSRIs are depression, anxiety, panic disorders, obsessive compulsive disorders, eating disorders and sometimes Post traumatic stress disorder (PTSD). However it should be remembered that all medications must be taken under medical supervision. i have had ocd now for 5 years i been on sertraline for about that time but last year all my unwanted throughts went away it was great for a year i stop taking my sertraline and then it came back i been back on the sertraline now for over 6months and i think it makes me worst i feels tension. Hi, I have suffered from GAD, Depression and OCD for over 30 years. In recent years, it had been fairly well controlled as I had started on Effexor XR over 300mg years back, and by 2014 had tapered down to 75mg per day. Last year suffered some trauma in a near fatal crash, and mentally did fine in the aftermath. Hi everyone, I take Sertraline for pure OCD /nasty intrusive thoughts & anxiety, depression etc. I have been on 150mg daily for the last 8 or so years. It has worked really well in reducing the frequency and intensity of the intrusive thoughts and suicidal feelings. However I have put on about 8 stone since being on them and just keep binging. I have always had binge eating disorder anyway, but it's definitely got significantly worse since being on sertraline,- I've never known cravings for sugar, chocolate and carbs like it - sometimes it's almost like some kind of primal survival instinct! I've had loads of counselling and CBT over the years and try as hard as I can to challenge the cravings and negative thoughts etc but something just takes over, if there is any trigger food in the vicinity (which I don't understand, because I feel like binge eating can be linked to an ocd anyway) Over the last few years, my communication and short term memory have declined which has been humiliating at work as I've screwed up meetings by fluffing my words, losing my train of thought and taking ages to 'get to the point' - plus forgetting things that people have literally just said!! I have the attention span of a gnat and freak out about what order to do tasks in. my mood has dropped, I'm around 20stone now and my confidence is rock bottom.
Int Clin Psychopharmacol. 1992 Oct;7 Suppl -41. Sertraline in the treatment of obsessive compulsive disorder two double-blind, placebo-controlled studies. Nausea or be sick vomit. Giving the medicine with some food or milk may help. • Your child may get diarrhoea or constipation difficulty